MyBioSource.com's Tri-methyl-Histone H4 (K20) Antibody monoclonal antibody. The Tri-methyl-Histone H4 (K20) Antibody was generated using HIST2H4B, HIST4H4, and histone cluster 4 H4 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Immunocytochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling